Pathogens:
Include bacteria, virus and fungi.
Pathogens are  micro-organisms that cause disease.
They cause disease by  penetrating or going through one of the interfaces with the environment,  e.g. skin, gas exchange system (mouth, nose, lungs are ideal for  bacterial growth/culture), the digestive system (food and water carrying  the pathogens in.)
Pathogens cause disease by either damaging host  tissues (Number of pathogens causes damage, like preventing them from  functioning properly, many pathogens can break down membranes, for  example.) Or, by producing toxins, which most bacterial pathogens do,  such as the cholera bacterium (vibiro cholorae) that leads to water loss  for the intestines.
1) A pathogen is a micro-organism that  causes disease
2) The digestive system and respiratory system is  often a site of entry for pathogens, as they are richly supplied with  blood vessels. Also, the body linings at these points are thin, moist  (sticky) and have a large surface area. So, overall, Blood vessels,  large surface area, thin, and moist (sticky.)
3) The two ways  pathogens cause disease are through, firstly, causing damage to the host  tissue. The sheer numbers of the pathogen could stop the cell from  functioning properly, such as breaking down the membrane. And, secondly,  by producing toxins, these could have an effect such as the cholera  bacterium, which causes water loss in the lining of the intestines.
4)  A reason why gastroenteritis/diarrhoea are not treated with oral  antibiotics, is because the main symptoms are diarrhoea and vomiting,  which would mean the antibiotic would be digested properly, and  therefore, wouldn’t have the desired effect.
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